Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
944572
TITLE
Genetic and environmental components of inconsistency and unrepeatability in twins' responses to a neuroticism questionnaire.
ABSTRACT
Responses of twins to an 11-item neuroticism scale extracted from questionnaires administered on two widely separated occasions were subjected to a genetic analysis. The results confirm earlier findings concerning the genetic determination of neuroticism and reveal that there is a genetic component in the inconsistency of the test measured by the interaction of subjects and test items. Variation within subjects over the 2-year period between tests was due purely to environmental factors specific to individuals. When a genetic model was fitted to the raw mean squares, there was no evidence that genetic variation was other than additive and no indication of an environmental component common to members of the same family.
DATE PUBLISHED
1976 Apr
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1976/04/01
medline 1976/04/01 00:01
entrez 1976/04/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Eaves L Eaves L L
Eysenck H Eysenck H H
INVESTIGATORS
JOURNAL
VOLUME: 6
ISSUE: 2
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 1976
MONTH: Apr
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Female
Genetics, Behavioral
Humans
Male
Neurotic Disorders genetics
Personality genetics
Phenotype genetics
Pregnancy genetics
Sex Factors genetics
Social Environment genetics
Surveys and Questionnaires genetics
Time Factors genetics
Twins genetics
Twins, Dizygotic genetics
Twins, Monozygotic genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's