Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
8741872
TITLE
Blood group chimerism in human multiple births is not rare.
ABSTRACT
Twin blood group chimerism seems to be very rare in humans. The 30-40 previously reported cases usually were found by mere coincidence during routine blood grouping in hospitals or blood banks. Usually in these cases frank blood group mixtures of, for example, 50/50%, 25/75%, or 5/95% at most were seen. Smaller percentages are very difficult to notice during routine work-up. Using a sensitive fluorescence technique (sensitivity > 0.01%) we detected blood group chimerism in 32/415 (8%) twin pairs and 12/57 (21%) triplet pairs, respectively, which is a higher incidence than reported previously.
DATE PUBLISHED
1996 Jan 22
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1996/01/22
medline 2000/06/20 09:00
entrez 1996/01/22 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
van Dijk BA van Dijk B A BA Blood Transfusion Department, University Hospital St. Radboud, Nijmegen, Netherlands.
Boomsma DI Boomsma D I DI
de Man AJ de Man A J AJ
INVESTIGATORS
JOURNAL
VOLUME: 61
ISSUE: 3
TITLE: American journal of medical genetics
ISOABBREVIATION: Am. J. Med. Genet.
YEAR: 1996
MONTH: Jan
DAY: 22
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0148-7299
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Am J Med Genet
COUNTRY: United States
ISSNLINKING: 0148-7299
NLMUNIQUEID: 7708900
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Blood Group Antigens
Child, Preschool
Chimera
Female
Fetofetal Transfusion
Humans
Male
Microscopy, Fluorescence
Pregnancy
Prospective Studies
Triplets
Twins, Dizygotic
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Blood Group Antigens
OTHER ID's