Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
8452193
TITLE
Aversive reactions and alcohol use in Europeans.
ABSTRACT
Two hundred subjects of European descent completed a questionnaire about alcohol use and reactions to alcohol. Eleven subjects (5.5%) reported that they always experienced unpleasant reactions after small amounts of alcohol, and these subjects reported significantly lower levels for quantity and frequency of habitual alcohol use, and fewer drinks in the preceding 7 days, than the other subjects. Reactions to alcohol, either genetic or acquired, can therefore be significant in determining alcohol use in non-Asian groups.
DATE PUBLISHED
1993 Feb
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1993/02/01
medline 1993/02/01 00:01
entrez 1993/02/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Whitfield JB Whitfield J B JB Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 17
ISSUE: 1
TITLE: Alcoholism, clinical and experimental research
ISOABBREVIATION: Alcohol. Clin. Exp. Res.
YEAR: 1993
MONTH: Feb
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0145-6008
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Alcohol Clin Exp Res
COUNTRY: England
ISSNLINKING: 0145-6008
NLMUNIQUEID: 7707242
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
AA 07535 NIAAA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Acetaldehyde pharmacokinetics
Adult pharmacokinetics
Alcohol Drinking genetics
Aldehyde Dehydrogenase deficiency
Cross-Cultural Comparison deficiency
Diseases in Twins genetics
Ethanol pharmacokinetics
Europe pharmacokinetics
Female pharmacokinetics
Flushing genetics
Humans genetics
Isoenzymes deficiency
Male deficiency
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Isoenzymes
3K9958V90M Ethanol
EC 1.2.1.3 Aldehyde Dehydrogenase
GO1N1ZPR3B Acetaldehyde
OTHER ID's