Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
8129693
TITLE
A third source of developmental differences.
ABSTRACT
An illustrative list is presented of human and animal studies which each point to the existence of a third source, in addition to genetic and environmental factors, underlying phenotypic differences in development. It is argued that this third source may consist of nonlinear epigenetic processes that can create variability at all phenotypical-somatic and behavioral-levels. In a quantitative genetic analysis with human subjects, these processes are confounded with within-family environmental influences. A preliminary model to quantify these influences is introduced.
DATE PUBLISHED
1993 Nov
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1993/11/01
medline 1993/11/01 00:01
entrez 1993/11/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Molenaar PC Molenaar P C PC University of Amsterdam, Department of Psychology, The Netherlands.
Boomsma DI Boomsma D I DI
Dolan CV Dolan C V CV
INVESTIGATORS
JOURNAL
VOLUME: 23
ISSUE: 6
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 1993
MONTH: Nov
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Review
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Animals
Genetics, Behavioral
Humans
Individuality
Models, Genetic
Nerve Net physiology
Phenotype physiology
Social Environment physiology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's