Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
QIMR Home Page
GenEpi Home Page
Publications
Contacts
Research
Staff Index
Collaborators
Software Tools
Computing Resources
Studies
Search
GenEpi Intranet
PMID
6685521
TITLE
Plasma lipids in twins. Environmental and genetic influences.
ABSTRACT
A study on 205 pairs of male and females twins, aged from 18 to 34 years. showed significant heritabilities for total and high density lipoprotein cholesterol and for triglycerides. Significant effects of shared environment were also found for total and HDL cholesterol, possibly to a greater extent in women than in men. Triglycerides showed greater variance in men but a model specifying different sized environmental and genetic parameters in the two sexes gave a good fit and indicated that the factors influencing plasma triglycerides are the same in men and women although the effects they produce are scaled differently.
DATE PUBLISHED
1983 Sep
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1983/09/01
medline 1983/09/01 00:01
entrez 1983/09/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Whitfield JB Whitfield J B JB
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 48
ISSUE: 3
TITLE: Atherosclerosis
ISOABBREVIATION: Atherosclerosis
YEAR: 1983
MONTH: Sep
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0021-9150
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Atherosclerosis
COUNTRY: Ireland
ISSNLINKING: 0021-9150
NLMUNIQUEID: 0242543
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Cholesterol blood
Cholesterol, HDL blood
Environment blood
Female blood
Genetic Variation blood
Humans blood
Lipids blood
Lipoproteins, HDL blood
Male blood
Models, Genetic blood
Pregnancy blood
Registries blood
Triglycerides blood
Twins blood
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Cholesterol, HDL
0 Lipids
0 Lipoproteins, HDL
0 Triglycerides
97C5T2UQ7J Cholesterol
OTHER ID's