Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
6541017
TITLE
The effects of inheritance on constituents of plasma: a twin study on some biochemical variables.
ABSTRACT
Heritability and within-person repeatability of thirteen constituents of plasma were assessed in a study of 206 pairs of male and female twins. Repeat measurements were available on 44 pairs. For bilirubin, calcium, creatinine, phosphate and potassium, the individuality of these characteristics was genetic in origin. Total protein, albumin and globulin showed significant heritability but considerable variation between occasions, while bicarbonate, chloride, iron, sodium and urea showed mainly environmental effects.
DATE PUBLISHED
1984 May
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1984/05/01
medline 1984/05/01 00:01
entrez 1984/05/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Whitfield JB Whitfield J B JB
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 21 ( Pt 3)
ISSUE:
TITLE: Annals of clinical biochemistry
ISOABBREVIATION: Ann. Clin. Biochem.
YEAR: 1984
MONTH: May
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0004-5632
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Ann Clin Biochem
COUNTRY: ENGLAND
ISSNLINKING: 0004-5632
NLMUNIQUEID: 0324055
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Bicarbonates blood
Bilirubin genetics
Blood Chemical Analysis genetics
Blood Proteins genetics
Calcium blood
Chlorides blood
Creatinine blood
Female blood
Humans blood
Iron blood
Male blood
Phosphates blood
Potassium blood
Pregnancy blood
Sodium blood
Twins blood
Urea blood
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Bicarbonates
0 Blood Proteins
0 Chlorides
0 Phosphates
8W8T17847W Urea
9NEZ333N27 Sodium
AYI8EX34EU Creatinine
E1UOL152H7 Iron
RFM9X3LJ49 Bilirubin
RWP5GA015D Potassium
SY7Q814VUP Calcium
OTHER ID's