Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
3440962
TITLE
Including the environment in models for genetic segregation.
ABSTRACT
Current models for linkage and segregation analysis do not allow for many of the different ways in which the environment may affect risk for a psychiatric disorder. A variety of mechanisms for the contribution of the environment and the correlation and interaction of environment effects with genetic differences are described. The approach to including these effects in models for segregation and linkage is outlined.
DATE PUBLISHED
1987
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1987/01/01
medline 1987/01/01 00:01
entrez 1987/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Eaves LJ Eaves L J LJ Department of Human Genetics, Medical College of Virginia, Richmond 23298.
INVESTIGATORS
JOURNAL
VOLUME: 21
ISSUE: 4
TITLE: Journal of psychiatric research
ISOABBREVIATION: J Psychiatr Res
YEAR: 1987
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0022-3956
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: J Psychiatr Res
COUNTRY: England
ISSNLINKING: 0022-3956
NLMUNIQUEID: 0376331
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, U.S. Gov't, P.H.S.
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
GM30250 NIGMS NIH HHS United States
GM32732 NIGMS NIH HHS United States
HL28922 NHLBI NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Genotype
Humans
Mental Disorders psychology
Models, Genetic psychology
Risk Factors psychology
Social Environment psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's