Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
26688007
TITLE
The association between childhood maltreatment, psychopathology, and adult sexual victimization in men and women: results from three independent samples.
ABSTRACT
BACKGROUND NlmCategory: BACKGROUND
Childhood maltreatment (CM) has consistently been linked with adverse outcomes including substance use disorders and adult sexual revictimization. Adult sexual victimization itself has been linked with psychopathology but has predominately been studied in women. The current investigation examines the impact of CM and co-occurring psychopathology on adult sexual victimization in men and women, replicating findings in three distinct samples.
METHOD NlmCategory: METHODS
We investigated the association between continuous CM factor scores and adult sexual victimization in the Childhood Trauma Study (CTS) sample (N = 2564). We also examined the unique relationship between childhood sexual abuse (CSA) and adult sexual victimization while adjusting for co-occurring substance dependence and psychopathology. We replicated these analyses in two additional samples: the Comorbidity and Trauma Study (CATS; N = 1981) and the Australian Twin-Family Study of Alcohol Use Disorders (OZ-ALC; N = 1537).
RESULTS NlmCategory: RESULTS
Analyses revealed a significant association with CM factor scores and adult sexual victimization for both men and women across all three samples. The CSA factor score was strongly associated with adult sexual victimization after adjusting for substance dependence and psychopathology; higher odds ratios were observed in men (than women) consistently across the three samples.
CONCLUSIONS NlmCategory: CONCLUSIONS
A continuous measure of CSA is independently associated with adult sexual trauma risk across samples in models that included commonly associated substance dependence and psychopathology as covariates. The strength of the association between this CSA measure and adult sexual victimization is higher in magnitude for men than women, pointing to the need for further investigation of sexual victimization in male community samples.
DATE PUBLISHED
2016 Feb
HISTORY
PUBSTATUS PUBSTATUSDATE
entrez 2015/12/22 06:00
pubmed 2015/12/22 06:00
medline 2015/12/22 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Werner KB Werner K B KB George Warren Brown School of Social Work,Washington University,St Louis,MO,USA.
McCutcheon VV McCutcheon V V VV Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Challa M Challa M M University of Illinois-Chicago School of Medicine,Chicago,IL,USA.
Agrawal A Agrawal A A Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Lynskey MT Lynskey M T MT Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
Conroy E Conroy E E Centre for Health Research,University of Western Sydney,Sydney,Australia.
Statham DJ Statham D J DJ QIMR Berghofer Medical Research Institute,Brisbane,Australia.
Madden PA Madden P A F PA Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Henders AK Henders A K AK National Drug and Alcohol Research Center,University of New South Wales,Sydney,Australia.
Todorov AA Todorov A A AA Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Heath AC Heath A C AC Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Degenhardt L Degenhardt L L National Drug and Alcohol Research Center,University of New South Wales,Sydney,Australia.
Martin NG Martin N G NG QIMR Berghofer Medical Research Institute,Brisbane,Australia.
Bucholz KK Bucholz K K KK Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
Nelson EC Nelson E C EC Alcoholism Research Center,Washington University School of Medicine,St Louis,MO,USA.
INVESTIGATORS
JOURNAL
VOLUME: 46
ISSUE: 3
TITLE: Psychological medicine
ISOABBREVIATION: Psychol Med
YEAR: 2016
MONTH: Feb
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1469-8978
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Psychol Med
COUNTRY: England
ISSNLINKING: 0033-2917
NLMUNIQUEID: 1254142
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
KEYWORD
Adult sexual revictimization
childhood sexual abuse
childhood trauma
psychopathology
sex disparities
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's