Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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26426971
TITLE
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
ABSTRACT
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.
DATE PUBLISHED
2015 Oct
HISTORY
PUBSTATUS PUBSTATUSDATE
ecollection 2015/10
received 2014/11/19
accepted 2015/06/22
epublish 2015/10/01
entrez 2015/10/02 06:00
pubmed 2015/10/02 06:00
medline 2015/10/02 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Winkler TW Winkler Thomas W TW Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany.
Justice AE Justice Anne E AE Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Graff M Graff Mariaelisa M Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Barata L Barata Llilda L Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Feitosa MF Feitosa Mary F MF Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Chu S Chu Su S Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Czajkowski J Czajkowski Jacek J Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Esko T Esko Tõnu T Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Fall T Fall Tove T Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.
Kilpeläinen TO Kilpeläinen Tuomas O TO Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Lu Y Lu Yingchang Y The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Mägi R Mägi Reedik R Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Mihailov E Mihailov Evelin E Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.
Pers TH Pers Tune H TH Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Rüeger S Rüeger Sina S Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
Teumer A Teumer Alexander A Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Ehret GB Ehret Georg B GB Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Ferreira T Ferreira Teresa T Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Heard-Costa NL Heard-Costa Nancy L NL Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America.
Karjalainen J Karjalainen Juha J University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.
Lagou V Lagou Vasiliki V Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom.
Mahajan A Mahajan Anubha A Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Neinast MD Neinast Michael D MD Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Prokopenko I Prokopenko Inga I Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London, United Kingdom.
Simino J Simino Jeannette J Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Teslovich TM Teslovich Tanya M TM Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Jansen R Jansen Rick R Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
Westra HJ Westra Harm-Jan HJ Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America.
White CC White Charles C CC Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Absher D Absher Devin D HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.
Ahluwalia TS Ahluwalia Tarunveer S TS Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Ahmad S Ahmad Shafqat S Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.
Albrecht E Albrecht Eva E Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Alves AC Alves Alexessander Couto AC Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom.
Bragg-Gresham JL Bragg-Gresham Jennifer L JL Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
de Craen AJ de Craen Anton J M AJ Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
Bis JC Bis Joshua C JC Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Bonnefond A Bonnefond Amélie A CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.
Boucher G Boucher Gabrielle G Montreal Heart Institute, Montréal, Québec, Canada.
Cadby G Cadby Gemma G Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia, Australia.
Cheng YC Cheng Yu-Ching YC VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America.
Chiang CW Chiang Charleston W K CW Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, United States of America.
Delgado G Delgado Graciela G Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Demirkan A Demirkan Ayse A Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Dueker N Dueker Nicole N Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland, United States of America.
Eklund N Eklund Niina N National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Eiriksdottir G Eiriksdottir Gudny G Icelandic Heart Association, Kopavogur, Iceland.
Eriksson J Eriksson Joel J Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Feenstra B Feenstra Bjarke B Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Fischer K Fischer Krista K Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.
Frau F Frau Francesca F Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.
Galesloot TE Galesloot Tessel E TE Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.
Geller F Geller Frank F Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Goel A Goel Anuj A Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Gorski M Gorski Mathias M Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Grammer TB Grammer Tanja B TB Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Gustafsson S Gustafsson Stefan S Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.
Haitjema S Haitjema Saskia S Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.
Hottenga JJ Hottenga Jouke-Jan JJ Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
Huffman JE Huffman Jennifer E JE National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.
Jackson AU Jackson Anne U AU Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Jacobs KB Jacobs Kevin B KB Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.
Johansson Å Johansson Åsa Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Kaakinen M Kaakinen Marika M Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland.
Kleber ME Kleber Marcus E ME Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Lahti J Lahti Jari J Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.
Mateo Leach I Mateo Leach Irene I University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.
Lehne B Lehne Benjamin B Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.
Liu Y Liu Youfang Y Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.
Lo KS Lo Ken Sin KS Montreal Heart Institute, Montréal, Québec, Canada.
Lorentzon M Lorentzon Mattias M Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Luan J Luan Jian'an J MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Madden PA Madden Pamela A F PA Washington University Medical School, St. Louis, Missouri, United States of America.
Mangino M Mangino Massimo M Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
McKnight B McKnight Barbara B Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Medina-Gomez C Medina-Gomez Carolina C Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Monda KL Monda Keri L KL Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America.
Montasser ME Montasser May E ME Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Müller G Müller Gabriele G Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Müller-Nurasyid M Müller-Nurasyid Martina M Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany.
Nolte IM Nolte Ilja M IM University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Panoutsopoulou K Panoutsopoulou Kalliope K Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.
Pascoe L Pascoe Laura L Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle, United Kingdom.
Paternoster L Paternoster Lavinia L MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
Rayner NW Rayner Nigel W NW Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.
Renström F Renström Frida F Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.
Rizzi F Rizzi Federica F Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.
Rose LM Rose Lynda M LM Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Ryan KA Ryan Kathy A KA Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Salo P Salo Perttu P National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland.
Sanna S Sanna Serena S Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.
Scharnagl H Scharnagl Hubert H Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Shi J Shi Jianxin J National Cancer Institute, Bethesda, Maryland, United States of America.
Smith AV Smith Albert Vernon AV Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Southam L Southam Lorraine L Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.
Stančáková A Stančáková Alena A Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Steinthorsdottir V Steinthorsdottir Valgerdur V deCODE Genetics, Amgen inc., Reykjavik, Iceland.
Strawbridge RJ Strawbridge Rona J RJ Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Sung YJ Sung Yun Ju YJ Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Tachmazidou I Tachmazidou Ioanna I Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.
Tanaka T Tanaka Toshiko T Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.
Thorleifsson G Thorleifsson Gudmar G deCODE Genetics, Amgen inc., Reykjavik, Iceland.
Trompet S Trompet Stella S Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Pervjakova N Pervjakova Natalia N Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki, Finland.
Tyrer JP Tyrer Jonathan P JP Department of Oncology, University of Cambridge, Cambridge, United Kingdom.
Vandenput L Vandenput Liesbeth L Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
van der Laan SW van der Laan Sander W SW Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.
van der Velde N van der Velde Nathalie N Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands.
van Setten J van Setten Jessica J Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands.
van Vliet-Ostaptchouk JV van Vliet-Ostaptchouk Jana V JV University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, The Netherlands.
Verweij N Verweij Niek N University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.
Vlachopoulou E Vlachopoulou Efthymia E Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.
Waite LL Waite Lindsay L LL HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.
Wang SR Wang Sophie R SR Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts, United States of America.
Wang Z Wang Zhaoming Z Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.
Wild SH Wild Sarah H SH Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Willenborg C Willenborg Christina C DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.
Wilson JF Wilson James F JF Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Wong A Wong Andrew A MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.
Yang J Yang Jian J Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Yengo L Yengo Loïc L CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.
Yerges-Armstrong LM Yerges-Armstrong Laura M LM Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Yu L Yu Lei L Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Zhang W Zhang Weihua W Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.
Zhao JH Zhao Jing Hua JH MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Andersson EA Andersson Ehm A EA Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bakker SJ Bakker Stephan J L SJ University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.
Baldassarre D Baldassarre Damiano D Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.
Banasik K Banasik Karina K Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Barcella M Barcella Matteo M Department of Health Sciences, University of Milan, Milan, Italy.
Barlassina C Barlassina Cristina C Department of Health Sciences, University of Milan, Milan, Italy.
Bellis C Bellis Claire C Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Benaglio P Benaglio Paola P Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Blangero J Blangero John J Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Blüher M Blüher Matthias M University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.
Bonnet F Bonnet Fabrice F University Rennes 1, Rennes, France.
Bonnycastle LL Bonnycastle Lori L LL Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.
Boyd HA Boyd Heather A HA Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Bruinenberg M Bruinenberg Marcel M University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen, The Netherlands.
Buchman AS Buchman Aron S AS Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Campbell H Campbell Harry H Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Chen YD Chen Yii-Der Ida YD Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Chines PS Chines Peter S PS Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.
Claudi-Boehm S Claudi-Boehm Simone S Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.
Cole J Cole John J VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.
Collins FS Collins Francis S FS Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.
de Geus EJ de Geus Eco J C EJ Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.
de Groot LC de Groot Lisette C P G M LC Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Dimitriou M Dimitriou Maria M Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.
Duan J Duan Jubao J NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.
Enroth S Enroth Stefan S Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Eury E Eury Elodie E CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.
Farmaki AE Farmaki Aliki-Eleni AE Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Forouhi NG Forouhi Nita G NG MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Friedrich N Friedrich Nele N Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Gejman PV Gejman Pablo V PV NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.
Gigante B Gigante Bruna B Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Glorioso N Glorioso Nicola N Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari, Italy.
Go AS Go Alan S AS Kaiser Permanente, Division of Research, Oakland, California, United States of America.
Gottesman O Gottesman Omri O The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Gräßler J Gräßler Jürgen J Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany.
Grallert H Grallert Harald H Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Grarup N Grarup Niels N Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Gu YM Gu Yu-Mei YM Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Broer L Broer Linda L Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Ham AC Ham Annelies C AC Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Hansen T Hansen Torben T Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Harris TB Harris Tamara B TB Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Hartman CA Hartman Catharina A CA University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands.
Hassinen M Hassinen Maija M Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
Hastie N Hastie Nicholas N MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.
Hattersley AT Hattersley Andrew T AT Institue of Biomedical & Clinical Science, University of Exeter, Exeter, United Kingdom.
Heath AC Heath Andrew C AC Washington University Medical School, St. Louis, Missouri, United States of America.
Henders AK Henders Anjali K AK QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.
Hernandez D Hernandez Dena D Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Hillege H Hillege Hans H University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.
Holmen O Holmen Oddgeir O Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
Hovingh KG Hovingh Kees G KG Department Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Hui J Hui Jennie J Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia.
Husemoen LL Husemoen Lise L LL Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark.
Hutri-Kähönen N Hutri-Kähönen Nina N Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere, Finland.
Hysi PG Hysi Pirro G PG Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Illig T Illig Thomas T Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover, Germany.
De Jager PL De Jager Philip L PL Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts,United States of America.
Jalilzadeh S Jalilzadeh Shapour S Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Jørgensen T Jørgensen Torben T Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark.
Jukema JW Jukema J Wouter JW Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.
Juonala M Juonala Markus M Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku, Finland.
Kanoni S Kanoni Stavroula S Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Karaleftheri M Karaleftheri Maria M Echinos Medical Centre, Echinos, Greece.
Khaw KT Khaw Kay Tee KT Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.
Kinnunen L Kinnunen Leena L Department of Health, National Institute for Health and Welfare, Helsinki, Finland.
Kittner SJ Kittner Steven J SJ VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.
Koenig W Koenig Wolfgang W Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.
Kolcic I Kolcic Ivana I Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.
Kovacs P Kovacs Peter P University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.
Krarup NT Krarup Nikolaj T NT Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kratzer W Kratzer Wolfgang W Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.
Krüger J Krüger Janine J Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Kuh D Kuh Diana D MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.
Kumari M Kumari Meena M Department of Epidemiology and Public Health, UCL, London, United Kingdom.
Kyriakou T Kyriakou Theodosios T Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Langenberg C Langenberg Claudia C MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London, United Kingdom.
Lannfelt L Lannfelt Lars L Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden.
Lanzani C Lanzani Chiara C Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan), Italy.
Lotay V Lotay Vaneet V Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.
Launer LJ Launer Lenore J LJ National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Leander K Leander Karin K Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Lindström J Lindström Jaana J Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.
Linneberg A Linneberg Allan A Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.
Liu YP Liu Yan-Ping YP Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Lobbens S Lobbens Stéphane S CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.
Luben R Luben Robert R Strangeways Research Laboratory Wort's Causeway, Cambridge, United Kingdom.
Lyssenko V Lyssenko Valeriya V Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden.
Männistö S Männistö Satu S National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.
Magnusson PK Magnusson Patrik K PK Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
McArdle WL McArdle Wendy L WL School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
Menni C Menni Cristina C Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Merger S Merger Sigrun S Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.
Milani L Milani Lili L Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.
Montgomery GW Montgomery Grant W GW QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.
Morris AP Morris Andrew P AP Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Narisu N Narisu Narisu N Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.
Nelis M Nelis Mari M Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.
Ong KK Ong Ken K KK MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.
Palotie A Palotie Aarno A Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts, United States of America.
Pérusse L Pérusse Louis L Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada.
Pichler I Pichler Irene I Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.
Pilia MG Pilia Maria G MG Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.
Pouta A Pouta Anneli A Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Rheinberger M Rheinberger Myriam M Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Ribel-Madsen R Ribel-Madsen Rasmus R Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Richards M Richards Marcus M MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.
Rice KM Rice Kenneth M KM Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Rice TK Rice Treva K TK Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Rivolta C Rivolta Carlo C Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Salomaa V Salomaa Veikko V National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.
Sanders AR Sanders Alan R AR NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.
Sarzynski MA Sarzynski Mark A MA Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.
Scholtens S Scholtens Salome S University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Scott RA Scott Robert A RA MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Scott WR Scott William R WR Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.
Sebert S Sebert Sylvain S Institute of Health Sciences, University of Oulu, Oulu, Finland.
Sengupta S Sengupta Sebanti S Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Sennblad B Sennblad Bengt B Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
Seufferlein T Seufferlein Thomas T Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.
Silveira A Silveira Angela A Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Slagboom PE Slagboom P Eline PE Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Smit JH Smit Jan H JH Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
Sparsø TH Sparsø Thomas H TH Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Stirrups K Stirrups Kathleen K Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Stolk RP Stolk Ronald P RP University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Stringham HM Stringham Heather M HM Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Swertz MA Swertz Morris A MA University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.
Swift AJ Swift Amy J AJ Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.
Syvänen AC Syvänen Ann-Christine AC Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Tan ST Tan Sian-Tsung ST Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Thorand B Thorand Barbara B Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Tönjes A Tönjes Anke A University of Leipzig, Department of Medicine, Leipzig, Germany.
Tremblay A Tremblay Angelo A Department of Kinesiology, Laval University, Québec City, Québec, Canada.
Tsafantakis E Tsafantakis Emmanouil E Anogia Medical Centre, Anogia, Greece.
van der Most PJ van der Most Peter J PJ University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Völker U Völker Uwe U Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Vohl MC Vohl Marie-Claude MC Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec,Canada.
Vonk JM Vonk Judith M JM University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Waldenberger M Waldenberger Melanie M DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Walker RW Walker Ryan W RW The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Wennauer R Wennauer Roman R Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany.
Widén E Widén Elisabeth E Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Willemsen G Willemsen Gonneke G Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
Wilsgaard T Wilsgaard Tom T Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Wright AF Wright Alan F AF MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.
Zillikens MC Zillikens M Carola MC Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
van Dijk SC van Dijk Suzanne C SC Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
van Schoor NM van Schoor Natasja M NM EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam, The Netherlands.
Asselbergs FW Asselbergs Folkert W FW Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London, United Kingdom.
de Bakker PI de Bakker Paul I W PI Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands.
Beckmann JS Beckmann Jacques S JS Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Beilby J Beilby John J Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia.
Bennett DA Bennett David A DA Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Bergman RN Bergman Richard N RN Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Bergmann S Bergmann Sven S Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Böger CA Böger Carsten A CA Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Boehm BO Boehm Bernhard O BO Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore, Singapore.
Boerwinkle E Boerwinkle Eric E Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America.
Boomsma DI Boomsma Dorret I DI Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
Bornstein SR Bornstein Stefan R SR Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Bottinger EP Bottinger Erwin P EP The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Bouchard C Bouchard Claude C Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.
Chambers JC Chambers John C JC Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.
Chanock SJ Chanock Stephen J SJ Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Chasman DI Chasman Daniel I DI Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.
Cucca F Cucca Francesco F Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari, Italy.
Cusi D Cusi Daniele D Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano, Italy.
Dedoussis G Dedoussis George G Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Erdmann J Erdmann Jeanette J DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.
Eriksson JG Eriksson Johan G JG National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
Evans DA Evans Denis A DA Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.
de Faire U de Faire Ulf U Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Farrall M Farrall Martin M Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.
Ferrucci L Ferrucci Luigi L Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.
Ford I Ford Ian I Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom.
Franke L Franke Lude L University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.
Franks PW Franks Paul W PW Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America.
Froguel P Froguel Philippe P CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.
Gansevoort RT Gansevoort Ron T RT University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.
Gieger C Gieger Christian C Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Grönberg H Grönberg Henrik H Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Gudnason V Gudnason Vilmundur V Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Gyllensten U Gyllensten Ulf U Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Hall P Hall Per P Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hamsten A Hamsten Anders A Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
van der Harst P van der Harst Pim P University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands.
Hayward C Hayward Caroline C MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.
Heliövaara M Heliövaara Markku M Department of Health, National Institute for Health and Welfare, Helsinki, Finland.
Hengstenberg C Hengstenberg Christian C DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.
Hicks AA Hicks Andrew A AA Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.
Hingorani A Hingorani Aroon A Institute of Cardiovascular Science, University College London, London, United Kingdom.
Hofman A Hofman Albert A Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Hu F Hu Frank F Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
Huikuri HV Huikuri Heikki V HV Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland.
Hveem K Hveem Kristian K Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
James AL James Alan L AL Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Jordan JM Jordan Joanne M JM Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.
Jula A Jula Antti A National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.
Kähönen M Kähönen Mika M Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.
Kajantie E Kajantie Eero E Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kathiresan S Kathiresan Sekar S Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Kiemeney LA Kiemeney Lambertus A L M LA Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen, The Netherlands.
Kivimaki M Kivimaki Mika M Department of Epidemiology and Public Health, UCL, London, United Kingdom.
Knekt PB Knekt Paul B PB National Institute for Health and Welfare, Helsinki, Finland.
Koistinen HA Koistinen Heikki A HA National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
Kooner JS Kooner Jaspal S JS Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.
Koskinen S Koskinen Seppo S Department of Health, National Institute for Health and Welfare, Helsinki, Finland.
Kuusisto J Kuusisto Johanna J Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Maerz W Maerz Winfried W Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Martin NG Martin Nicholas G NG QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.
Laakso M Laakso Markku M Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Lakka TA Lakka Timo A TA Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.
Lehtimäki T Lehtimäki Terho T Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland.
Lettre G Lettre Guillaume G Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.
Levinson DF Levinson Douglas F DF Stanford University, Stanford, California, United States of America.
Lind L Lind Lars L Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Lokki ML Lokki Marja-Liisa ML Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.
Mäntyselkä P Mäntyselkä Pekka P Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
Melbye M Melbye Mads M Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
Metspalu A Metspalu Andres A Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.
Mitchell BD Mitchell Braxton D BD University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America.
Moll FL Moll Frans L FL Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
Murray JC Murray Jeffrey C JC Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.
Musk AW Musk Arthur W AW Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Nieminen MS Nieminen Markku S MS HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.
Njølstad I Njølstad Inger I Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Ohlsson C Ohlsson Claes C Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Oldehinkel AJ Oldehinkel Albertine J AJ University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen, The Netherlands.
Oostra BA Oostra Ben A BA Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Palmer LJ Palmer Lyle J LJ School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.
Pankow JS Pankow James S JS Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Pasterkamp G Pasterkamp Gerard G Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.
Pedersen NL Pedersen Nancy L NL Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Pedersen O Pedersen Oluf O Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Penninx BW Penninx Brenda W BW Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
Perola M Perola Markus M Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Peters A Peters Annette A DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Polašek O Polašek Ozren O Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.
Pramstaller PP Pramstaller Peter P PP Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano, Italy.
Psaty BM Psaty Bruce M BM Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington, United States of America.
Qi L Qi Lu L Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
Quertermous T Quertermous Thomas T Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
Raitakari OT Raitakari Olli T OT Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Rankinen T Rankinen Tuomo T Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.
Rauramaa R Rauramaa Rainer R Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
Ridker PM Ridker Paul M PM Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.
Rioux JD Rioux John D JD Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.
Rivadeneira F Rivadeneira Fernando F Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Rotter JI Rotter Jerome I JI Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Rudan I Rudan Igor I Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
den Ruijter HM den Ruijter Hester M HM Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.
Saltevo J Saltevo Juha J Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.
Sattar N Sattar Naveed N BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.
Schunkert H Schunkert Heribert H DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.
Schwarz PE Schwarz Peter E H PE Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Shuldiner AR Shuldiner Alan R AR Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, United States of America.
Sinisalo J Sinisalo Juha J HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.
Snieder H Snieder Harold H University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.
Sørensen TI Sørensen Thorkild I A TI Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.
Spector TD Spector Tim D TD Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Staessen JA Staessen Jan A JA Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht, The Netherlands.
Stefania B Stefania Bandinelli B Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.
Thorsteinsdottir U Thorsteinsdottir Unnur U deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Stumvoll M Stumvoll Michael M University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.
Tardif JC Tardif Jean-Claude JC Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.
Tremoli E Tremoli Elena E Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.
Tuomilehto J Tuomilehto Jaakko J Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
Uitterlinden AG Uitterlinden André G AG Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Uusitupa M Uusitupa Matti M Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.
Verbeek AL Verbeek André L M AL Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.
Vermeulen SH Vermeulen Sita H SH Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands.
Viikari JS Viikari Jorma S JS Department of Medicine, University of Turku, Turku, Finland.
Vitart V Vitart Veronique V MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.
Völzke H Völzke Henry H Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Vollenweider P Vollenweider Peter P Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.
Waeber G Waeber Gérard G Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.
Walker M Walker Mark M Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.
Wallaschofski H Wallaschofski Henri H Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Wareham NJ Wareham Nicholas J NJ MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Watkins H Watkins Hugh H Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Zeggini E Zeggini Eleftheria E Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.
CHARGE Consortium
DIAGRAM Consortium
GLGC Consortium
Global-BPGen Consortium
ICBP Consortium
MAGIC Consortium
Chakravarti A Chakravarti Aravinda A Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Clegg DJ Clegg Deborah J DJ Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Cupples LA Cupples L Adrienne LA National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Gordon-Larsen P Gordon-Larsen Penny P Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Jaquish CE Jaquish Cashell E CE National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, United States of America.
Rao DC Rao D C DC Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Abecasis GR Abecasis Goncalo R GR Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Assimes TL Assimes Themistocles L TL Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
Barroso I Barroso Inês I Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom.
Berndt SI Berndt Sonja I SI Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Boehnke M Boehnke Michael M Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
Deloukas P Deloukas Panos P Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
Fox CS Fox Caroline S CS National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.
Groop LC Groop Leif C LC Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland.
Hunter DJ Hunter David J DJ Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.
Ingelsson E Ingelsson Erik E Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
Kaplan RC Kaplan Robert C RC Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.
McCarthy MI McCarthy Mark I MI Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom.
Mohlke KL Mohlke Karen L KL Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
O'Connell JR O'Connell Jeffrey R JR Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Schlessinger D Schlessinger David D National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Strachan DP Strachan David P DP Population Health Research Institute, St George's, University of London, London, United Kingdom.
Stefansson K Stefansson Kari K deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
van Duijn CM van Duijn Cornelia M CM Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands.
Hirschhorn JN Hirschhorn Joel N JN Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Lindgren CM Lindgren Cecilia M CM Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Heid IM Heid Iris M IM Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
North KE North Kari E KE Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Borecki IB Borecki Ingrid B IB Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Kutalik Z Kutalik Zoltán Z Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Loos RJ Loos Ruth J F RJ MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
INVESTIGATORS
JOURNAL
VOLUME: 11
ISSUE: 10
TITLE: PLoS genetics
ISOABBREVIATION: PLoS Genet.
YEAR: 2015
MONTH: Oct
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1553-7404
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: PLoS Genet
COUNTRY: United States
ISSNLINKING: 1553-7390
NLMUNIQUEID: 101239074
PUBLICATION TYPE
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Journal Article
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTID AGENCY COUNTRY
P30 AG010161 NIA NIH HHS United States
GENERAL NOTE
KEYWORDS
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SUPPLEMENTARY MESH
GENE SYMBOLS
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OTHER ID's
OTHERID SOURCE
PMC4591371 NLM