Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
25171127
TITLE
Telescoping and gender differences in the time course of disordered gambling: evidence from a general population sample.
ABSTRACT
BACKGROUND AND AIM NlmCategory: OBJECTIVE
The course of disordered gambling in women has been described as 'telescoped' compared with that in men, with a later age at initiation of gambling but shorter times from initiation to disorder. This study examined the evidence, for the first time, for such a telescoping effect in a general population rather than a treatment-seeking sample.
METHOD NlmCategory: METHODS
Participants in a large community-based Australian twin cohort (2001 men, 2662 women) were assessed by structured diagnostic telephone interviews in which they reported the ages at which they had attained various gambling milestones and additional information to be used as covariates (the types of gambling in which they had participated and history of symptoms of alcohol dependence, major depression, and adult antisocial behavior). Cox proportional hazards regression models were used to examine differences between men and women in the time from gambling initiation to the first disordered gambling symptom and a diagnosis of disordered gambling.
RESULTS NlmCategory: RESULTS
Men had a higher hazards than women for the time to the first disordered gambling symptom [hazard ratio (HR) = 3.13, P < 0.0001] and to a diagnosis of disordered gambling (HR = 2.53, P < 0.0001). These differences persisted after controlling for covariates. Earlier age of initiation was the most potent predictor of progression to the first symptom.
CONCLUSIONS NlmCategory: CONCLUSIONS
When assessed at the general population level, female gamblers do not appear to show a telescoped disordered gambling trajectory compared with male gamblers.
2014 Society for the Study of Addiction.
DATE PUBLISHED
2015 Jan
HISTORY
PUBSTATUS PUBSTATUSDATE
received 2014/03/25
revised 2014/06/23
accepted 2014/08/19
aheadofprint 2014/10/16
entrez 2014/08/30 06:00
pubmed 2014/08/30 06:00
medline 2014/08/30 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Slutske WS Slutske Wendy S WS University of Missouri, Columbia, MO, USA; Midwest Alcoholism Research Center, Columbia, MO, USA.
Piasecki TM Piasecki Thomas M TM
Deutsch AR Deutsch Arielle R AR
Statham DJ Statham Dixie J DJ
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 110
ISSUE: 1
TITLE: Addiction (Abingdon, England)
ISOABBREVIATION: Addiction
YEAR: 2015
MONTH: Jan
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1360-0443
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Addiction
COUNTRY: England
ISSNLINKING: 0965-2140
NLMUNIQUEID: 9304118
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
MH66206 NIMH NIH HHS United States
R01 MH066206 NIMH NIH HHS United States
GENERAL NOTE
KEYWORDS
KEYWORD
Age of onset
disordered gambling
gambling initiation
sex differences
telescoping
trajectory
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS625802 NLM
PMC4270904 NLM