Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
21918574
TITLE
Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.
ABSTRACT
DATE PUBLISHED
2012 Jan
HISTORY
PUBSTATUS PUBSTATUSDATE
aheadofprint 2011/09/15
entrez 2011/09/16 06:00
pubmed 2011/09/16 06:00
medline 2012/04/13 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Rao F Rao Fangwen F Department of Medicine, University of California, San Diego, CA, USA.
Chiron S Chiron Stephane S
Wei Z Wei Zhiyun Z
Fung MM Fung Maple M MM
Chen Y Chen Yuqing Y
Wen G Wen Gen G
Khandrika S Khandrika Srikrishna S
Ziegler MG Ziegler Michael G MG
Benyamin B Benyamin Beben B
Montgomery G Montgomery Grant G
Whitfield JB Whitfield John B JB
Martin NG Martin Nicholas G NG
Waalen J Waalen Jill J
Hamilton BA Hamilton Bruce A BA
Mahata SK Mahata Sushil K SK
O'Connor DT O'Connor Daniel T DT
INVESTIGATORS
JOURNAL
MEDLINE JOURNAL
MEDLINETA: Am J Hypertens
COUNTRY: United States
ISSNLINKING: 0895-7061
NLMUNIQUEID: 8803676
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
KL2 TR000099 NCATS NIH HHS United States
MD000220 NIMHD NIH HHS United States
P01 HL058120 NHLBI NIH HHS United States
P60 MD000220 NIMHD NIH HHS United States
R01 DK094894 NIDDK NIH HHS United States
RR00827 NCRR NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Aged
Aged, 80 and over
Body Mass Index
C-Reactive Protein genetics
Chromaffin Cells metabolism
Chromogranin A genetics
Female genetics
Genetic Pleiotropy genetics
Humans genetics
Leptin genetics
Male genetics
Metabolic Syndrome X genetics
Middle Aged genetics
Polymorphism, Genetic genetics
Promoter Regions, Genetic genetics
Risk genetics
Twins, Dizygotic genetics
Twins, Monozygotic genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 CHGA protein, human
0 Chromogranin A
0 Leptin
9007-41-4 C-Reactive Protein
OTHER ID's
OTHERID SOURCE
NIHMS455832 NLM
PMC3664223 NLM