Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
19878140
TITLE
H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence.
ABSTRACT
DATE PUBLISHED
2010 Jan
HISTORY
PUBSTATUS PUBSTATUSDATE
aheadofprint 2009/10/29
entrez 2009/11/03 06:00
pubmed 2009/11/03 06:00
medline 2010/03/17 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Nelson EC Department of Psychiatry, Washington University School of Medicine, USA.
Agrawal A
Pergadia ML
Wang JC
Whitfield JB
Saccone FS
Kern J
Grant JD
Schrage AJ
Rice JP
Montgomery GW
Heath AC
Goate AM
Martin NG
Madden PA
INVESTIGATORS
JOURNAL
MEDLINE JOURNAL
MEDLINETA: Addict Biol
COUNTRY: United States
ISSNLINKING: 1355-6215
NLMUNIQUEID: 9604935
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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CommentIn Addict Biol. 2010 Jan;15(1):12-4 20002019
GRANTS
GRANTID AGENCY COUNTRY
AA007728 NIAAA NIH HHS United States
AA011998 NIAAA NIH HHS United States
AA013446 NIAAA NIH HHS United States
AA017688 NIAAA NIH HHS United States
DA012854 NIDA NIH HHS United States
K05 AA017688 NIAAA NIH HHS United States
K05 AA017688-02 NIAAA NIH HHS United States
P60 AA011998 NIAAA NIH HHS United States
P60 AA011998-11 NIAAA NIH HHS United States
R01 AA013446-05 NIAAA NIH HHS United States
R01 DA012854 NIDA NIH HHS United States
R01 DA012854-07 NIDA NIH HHS United States
R37 AA007728 NIAAA NIH HHS United States
R37 AA007728-20 NIAAA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Alcoholism psychology
Alleles psychology
Child psychology
Child Abuse, Sexual statistics & numerical data
Chromosome Inversion genetics
Chromosomes, Human, Pair 17 genetics
Cohort Studies genetics
Comorbidity genetics
Diseases in Twins psychology
European Continental Ancestry Group genetics
Female genetics
Gene Frequency genetics
Genetic Predisposition to Disease psychology
Genotype psychology
Haplotypes genetics
Heterozygote Detection genetics
Histocompatibility Antigens Class II genetics
Humans genetics
Life Change Events genetics
Linkage Disequilibrium genetics
Male genetics
Middle Aged genetics
Polymorphism, Single Nucleotide genetics
Receptors, Corticotropin-Releasing Hormone genetics
Risk Factors genetics
Smoking psychology
Social Environment psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 CRF receptor type 1
0 Histocompatibility Antigens Class II
0 Receptors, Corticotropin-Releasing Hormone
OTHER ID's
OTHERID SOURCE
NIHMS278335 NLM
PMC3068622 NLM