Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
1793427
TITLE
A model for comparative ratings in studies of within-family differences.
ABSTRACT
Comparative ratings between pairs of siblings or other relatives are commonly used to refine measures of intrafamily variation. A simple model, based on signal detection theory, is proposed which shows how comparative ratings can be used to estimate within-pair variances of true scores, which can, in turn, be modeled with any of the conventional approaches to partitioning genetic and environmental variance within families.
DATE PUBLISHED
1991 Nov
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1991/11/01
medline 1991/11/01 00:01
entrez 1991/11/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Eaves LJ Eaves L J LJ Department of Human Genetics, Medical College of Virginia, Richmond 23298.
Neale MC Neale M C MC
Meyer JM Meyer J M JM
INVESTIGATORS
JOURNAL
VOLUME: 21
ISSUE: 6
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 1991
MONTH: Nov
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, U.S. Gov't, P.H.S.
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
GM-30250 NIGMS NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Humans
Models, Genetic
Personality genetics
Phenotype genetics
Social Environment genetics
Twins psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's