Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
16502139
TITLE
Genetic factors in physical activity and the equal environment assumption-- the Swedish young male twins study.
ABSTRACT
The aims of this study were to examine the genetic contribution on physical activity (PA) within a nationwide population of young adult male twin pairs from Sweden and to investigate the equal environment assumption (EEA) in relation to PA. Information on PA was collected by questionnaires in 1998 and 2002 and the impact of genetic factors was estimated by structural equation modeling (SEM). The study included 1,022 pairs of twins and the best fitting SEM-model gave a heritability of 49% (95% CI, 40-56%) for total PA and all PA dimensions showed genetic contributions between 40% and 65%. Non-shared environmental factors were also important, whereas shared environmental factors did not contribute to PA behaviors. The EEA was investigated with a linear regression model, examining if the twins contact frequency predicted within-pair differences in PA, and further by a simulation study. We found no support for violation of the EEA.
DATE PUBLISHED
2006 Mar
HISTORY
PUBSTATUS PUBSTATUSDATE
received 2005/06/22
accepted 2005/09/08
pubmed 2006/02/28 09:00
medline 2006/10/13 09:00
entrez 2006/02/28 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Eriksson M Eriksson Marit M The Child and Adolescent Public Health Epidemiology Group, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Rasmussen F Rasmussen Finn F
Tynelius P Tynelius Per P
INVESTIGATORS
JOURNAL
VOLUME: 36
ISSUE: 2
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 2006
MONTH: Mar
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Body Mass Index
Exercise psychology
Humans psychology
Linear Models psychology
Longitudinal Studies psychology
Male psychology
Phenotype psychology
Social Environment psychology
Statistics as Topic psychology
Sweden psychology
Twins, Dizygotic psychology
Twins, Monozygotic psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's