Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
12415317
TITLE
Classical twin studies and beyond.
ABSTRACT
Twin studies have been a valuable source of information about the genetic basis of complex traits. To maximize the potential of twin studies, large, worldwide registers of data on twins and their relatives have been established. Here, we provide an overview of the current resources for twin research. These can be used to obtain insights into the genetic epidemiology of complex traits and diseases, to study the interaction of genotype with sex, age and lifestyle factors, and to study the causes of co-morbidity between traits and diseases. Because of their design, these registers offer unique opportunities for selected sampling for quantitative trait loci linkage and association studies.
DATE PUBLISHED
2002 Nov
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2002/11/05 04:00
medline 2002/12/19 04:00
entrez 2002/11/05 04:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Boomsma D Boomsma Dorret D Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands. di.boomsma@psy.vu.nl
Busjahn A Busjahn Andreas A
Peltonen L Peltonen Leena L
INVESTIGATORS
JOURNAL
VOLUME: 3
ISSUE: 11
TITLE: Nature reviews. Genetics
ISOABBREVIATION: Nat. Rev. Genet.
YEAR: 2002
MONTH: Nov
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1471-0056
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Nat Rev Genet
COUNTRY: England
ISSNLINKING: 1471-0056
NLMUNIQUEID: 100962779
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Review
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Female
Genetic Research
Humans
Male
Pedigree
Twin Studies as Topic methods
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's